Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.44 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.44 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.44 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.44 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.44 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.44 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.44 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31164338 | 1.00 | CYP19A1 (0.48) | CYP19A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL10405242 | 1.00 | CYP19A1 (0.48) | CYP19A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL27559513 | 0.86 | CYP19A1 (0.51) | CYP19A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL10404371 | 0.86 | CYP19A1 (0.51) | CYP19A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL4996284 | 0.86 | CYP19A1 (0.51) | CYP19A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL4996289 | 0.86 | CYP19A1 (0.51) | CYP19A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL9157639 | 0.83 | GABRA1 (0.53) | SHBGMEN1KMT2A | |
| SCHEMBL9157631 | 0.83 | GABRA1 (0.53) | SHBGMEN1KMT2A | |
| SCHEMBL14154560 | 0.82 | SERPINA6 (0.62) | SHBGLMNAHSD17B10GPBAR1SERPINA6 | |
| SCHEMBL9160261 | 0.82 | SERPINA6 (0.62) | SHBGLMNAHSD17B10GPBAR1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898694-A | 17-Hydroxy-steroids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1990-02-06 | — | — | US | disclosed |