Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404478 | 0.89 | KDM4E (0.34) | APEX1GLSALDH1A1GAAL3MBTL1 | |
| SCHEMBL10403063 | 0.79 | KDM4E (0.40) | APEX1GLSALDH1A1GAAL3MBTL1 | |
| SCHEMBL10402745 | 0.78 | HSD17B10 (0.43) | APEX1ALDH1A1GAAL3MBTL1HPGD | |
| SCHEMBL10403061 | 0.76 | KDM4E (0.40) | APEX1GLSALDH1A1GAAL3MBTL1 | |
| SCHEMBL10401908 | 0.76 | KDM4E (0.41) | APEX1GLSALDH1A1KDM4ETDP1 | |
| SCHEMBL10404083 | 0.74 | GAA (0.62) | APEX1ALDH1A1GAAL3MBTL1HPGD | |
| SCHEMBL10403434 | 0.74 | KMT2A (0.37) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL10403614 | 0.71 | ALDH1A1 (0.32) | APEX1ALDH1A1KDM4E | |
| SCHEMBL10767752 | 0.69 | — | — | |
| SCHEMBL11657270 | 0.64 | HTR7 (0.55) | APEX1ALDH1A1KDM4ETDP1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |