Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 4/20 | 0.57 |
| ▸ | MTTP | P55157 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405919 | 0.89 | ALDH1A1 (0.61) | APOBMTTPMEN1KMT2ANR1H2 | |
| SCHEMBL10405720 | 0.85 | APOB (0.51) | APOBMTTPMEN1KMT2ANR1H2 | |
| SCHEMBL10405769 | 0.84 | MEN1 (0.52) | APOBMTTPMEN1KMT2ANR1H2 | |
| SCHEMBL10405772 | 0.84 | MEN1 (0.52) | APOBMTTPMEN1KMT2ANR1H2 | |
| SCHEMBL5822058 | 0.82 | PSEN1 (0.65) | APOBMTTPMEN1KMT2APSEN1 | |
| SCHEMBL10405664 | 0.81 | NR1H2 (0.48) | APOBMTTPMEN1KMT2ANR1H2 | |
| SCHEMBL10406159 | 0.81 | APOB (0.48) | APOBMTTPMEN1KMT2ANR1H2 | |
| SCHEMBL4733742 | 0.80 | NR1H2 (0.55) | APOBMTTPMEN1KMT2ANR1H2 | |
| SCHEMBL10406586 | 0.80 | TBXA2R (0.65) | APOBMTTPMEN1KMT2ANR1H2 | |
| SCHEMBL7760828 | 0.80 | PSEN1 (0.71) | APOBMTTPMEN1KMT2ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929754-A | CARDIOVASCULAR DISORDERS, ANTICOAGULANTS, ANTITUMOR AGENTS | DR. KARL THOMAE GMBH (DE) | 1990-05-29 | — | — | US | disclosed |
| US-4820705-A | ANTITUMOR, CARDIOVASCULR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1989-04-11 | — | — | US | disclosed |