SCHEMBL10406497

SCHEMBL10406497

C[C](C)CC1CCC(O)CC1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.37
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL349125 0.88
SCHEMBL15067035 0.79 EPHX2 (0.36) SHBGTSHR
SCHEMBL12166729 0.79 SHBG (0.34) SHBGTSHR
SCHEMBL8610931 0.78 POLB (0.33)
SCHEMBL8608382 0.78 NAMPT (0.31)
SCHEMBL10406536 0.77 CYP3A4 (0.33)
SCHEMBL5688 0.77
SCHEMBL5021 0.77
SCHEMBL28166023 0.76 KDM1A (0.31)
SCHEMBL10406220 0.75 CYP3A4 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104136411-A therapeutically active compounds and methods of use thereof AGIOS PHARMACEUTICALS INC 2014-11-05 CN disclosed
CN-101180298-B Antibiotic derivatives ACTELION PHARMACEUTICALS LTD 2011-04-27 CN disclosed
US-4935426-A FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1990-06-19 US disclosed