SCHEMBL1040663

SCHEMBL1040663

CCNCc1ccccn1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.61
MAOA P21397 3/20 0.55
MAOB P27338 3/20 0.55
SMN1; SMN2 Q16637 1/20 0.53
KDM4E B2RXH2 3/20 0.53
SCN8A Q9UQD0 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
HRH3 Q9Y5N1 1/20 0.50
SIRT2 Q8IXJ6 1/20 0.49
ALOX15 P16050 3/20 0.48
ALDH1A1 P00352 3/20 0.48
LMNA P02545 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
TSHR P16473 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28386195 0.98 CHRM2 (0.59) CHRM2MAOAMAOBSMN1; SMN2KDM4E
SCHEMBL28390369 0.89 LMNA (0.58) CHRM2SMN1; SMN2KDM4EL3MBTL1ALDH1A1
SCHEMBL29438821 0.87 CHRM2 (0.70) CHRM2MAOAMAOBSMN1; SMN2KDM4E
SCHEMBL230222 0.87 CHRM2 (0.70) CHRM2MAOAMAOBSMN1; SMN2KDM4E
SCHEMBL25211342 0.85 CHRM2 (0.68) CHRM2MAOAMAOBSMN1; SMN2KDM4E
SCHEMBL317984 0.85 CHRM2 (0.68) CHRM2MAOAMAOBSMN1; SMN2KDM4E
Zinc Ion SCHEMBL30442739 0.85 CHRM2 (0.68) CHRM2MAOAMAOBSMN1; SMN2KDM4E
Zinc Ion SCHEMBL30205248 0.85 CHRM2 (0.68) CHRM2MAOAMAOBSMN1; SMN2KDM4E
SCHEMBL18493706 0.85 CHRM2 (0.68) CHRM2MAOAMAOBSMN1; SMN2KDM4E
SCHEMBL434742 0.84 CHRM2 (0.68) CHRM2MAOAMAOBSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110831640-A Gas delivery device 密歇根大学董事会 2020-02-21 CN claimed
US-7332514-B2 Dibenzylamine compound and medicinal use thereof JAPAN TOBACCO INC. (JP) 2008-02-19 US claimed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US disclosed
CN-119013244-A Process for the hydrogenation of unsaturated esters 庄信万丰股份有限公司 2024-11-22 CN disclosed
US-12024549-B2 Compound having affinity substance to soluble protein, cleavable portion and reactive group, or salt thereof AJINOMOTO CO., INC. (JP) 2024-07-02 US disclosed
CN-117624031-A Preparation method of 4- (ethylaminomethyl) pyridine 安徽华邦药业有限公司 2024-03-01 CN disclosed
US-11912714-B2 Spiropyrrolidine derived antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2024-02-27 US disclosed
US-20240010915-A1 Etching Solution For Titanium Nitride And Molybdenum Conductive Metal Lines VERSUM MATERIALS US, LLC (US) 2024-01-11 US disclosed
CN-117362219-A Preparation method of 4- (ethylaminomethyl) pyridine 南京法恩化学有限公司 2024-01-09 CN disclosed
CN-117083259-A Selective catalytic olefin isomerization for the manufacture of perfume ingredients or intermediates 国际香精香料公司 2023-11-17 CN disclosed
CN-114206948-B catheter insertion device 密歇根大学董事会 2023-11-03 CN disclosed
US-6093714-A AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS MEIJI SEIKA KAISHA, LTD. (JP) 2000-07-25 US disclosed
WO-1999033800-A1 INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 1999-07-08 WO disclosed
US-5872257-A CHELATING LIGANDS FOR FROMING COORDINATION COMPLEXES WITH METAL IN LIQUID AND SUPERCRITICAL CARBONDIOXIDE OF COVELENTLY BONDED GROUPS SELECTED FORM DITHIOCARBAMATE, PICOLYLAMINE, THIOL, A SPACERS AND FLUOROALKYLOXY OR FLUOROMETHYLENE UNIVERSITY OF PITTSBURGH (US) 1999-02-16 US disclosed
CN-1190971-A Tricyclic benzazepine * compounds MEIJI SEIKA CO (JP) 1998-08-19 CN disclosed
EP-0834512-A1 TRICYCLIC BENZAZEPINE COMPOUNDS MEIJI SEIKA KAISHA LTD. (JP) 1998-04-08 EP disclosed
US-5354866-A Treating HIV infections ABBOTT LABORATORIES (US) 1994-10-11 US disclosed
EP-0366085-A2 Tetrahydropyrimidines, their production and use Takeda Chemical Industries, Ltd. (JP) 1990-05-02 EP disclosed
US-4097481-A ANTIARRHYTHMIC AGENTS RIKER LABORATORIES, INC. (US) 1978-06-27 US disclosed
US-4006239-A Benzoic acid amides for mycobacterium infections BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12024549-B2 Compound having affinity substance to soluble protein, cleavable portion and reactive group, or salt thereof SPPL2B, CSTB, SPPL2A CHRM2 3962/4885MAOA 1651/4885MAOB 1018/4885
US-11912714-B2 Spiropyrrolidine derived antiviral agents ACE, ACE2, PKD1 CHRM2 4110/4885MAOA 2508/4885MAOB 2323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.