Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407835 | 0.84 | TRPV1 (0.35) | HTTTRPV1KDM4EALDH1A1GAA | |
| SCHEMBL15732095 | 0.82 | KCNE1 (0.38) | HTTTRPV1KCNE1KCNQ1LMNA | |
| SCHEMBL24090503 | 0.81 | TRPV1 (0.37) | HTTTRPV1KCNE1KCNQ1LMNA | |
| SCHEMBL7913673 | 0.81 | HTR2A (0.39) | HTTTRPV1KCNE1KCNQ1LMNA | |
| Alcohol SCHEMBL10531474 | 0.79 | KCNE1 (0.42) | HTTTRPV1KCNE1KCNQ1LMNA | |
| SCHEMBL17061216 | 0.79 | PTGDR2 (0.44) | TRPV1ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL3580439 | 0.78 | MEN1 (0.43) | HTTTRPV1KCNE1KCNQ1LMNA | |
| SCHEMBL15021653 | 0.78 | MEN1 (0.43) | HTTTRPV1KCNE1KCNQ1LMNA | |
| SCHEMBL31253977 | 0.78 | MEN1 (0.43) | HTTTRPV1KCNE1KCNQ1LMNA | |
| SCHEMBL13573386 | 0.78 | MEN1 (0.43) | HTTTRPV1KCNE1KCNQ1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977166-A | ANTIARRHYTHMIC AND ANTIFIBRILLATORY AGENTS | RHONE-POULENC SANTE (FR) | 1990-12-11 | — | — | US | disclosed |