Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.66 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130424 | 0.88 | QDPR (0.76) | QDPRCA2NR3C1ALOX5PTPN1 | |
| SCHEMBL10407587 | 0.87 | QDPR (0.65) | QDPRHTR2CPDE4B | |
| SCHEMBL2473309 | 0.85 | PDE4B (0.64) | QDPRNR3C1HTR2CPDE4BALDH1A1 | |
| Hydrochloric Acid SCHEMBL9014415 | 0.83 | PDE4B (0.62) | QDPRNR3C1HTR2CPDE4BALDH1A1 | |
| Hydrochloric Acid SCHEMBL9772895 | 0.83 | PDE4B (0.62) | QDPRNR3C1HTR2CPDE4BALDH1A1 | |
| SCHEMBL8864091 | 0.83 | QDPR (0.69) | QDPRCA2NR3C1ALOX5PTPN1 | |
| SCHEMBL14632138 | 0.83 | HTR2A (0.65) | QDPRCA2NR3C1HTR2CPDE4B | |
| SCHEMBL310290 | 0.82 | HTR2C (0.55) | QDPRNR3C1HTR2CPDE4BTSHR | |
| SCHEMBL13062522 | 0.81 | QDPR (0.61) | QDPRCA2NR3C1ALOX5PTPN1 | |
| SCHEMBL5584961 | 0.81 | HTR2A (0.58) | QDPRHTR2CPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977166-A | ANTIARRHYTHMIC AND ANTIFIBRILLATORY AGENTS | RHONE-POULENC SANTE (FR) | 1990-12-11 | — | — | US | disclosed |