SCHEMBL8864091

SCHEMBL8864091

COc1cc(C2CCCCC2)ccc1O

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
QDPR P09417 2/20 0.69
CA2 P00918 2/20 0.62
NR3C1 P04150 2/20 0.62
TSHR P16473 1/20 0.60
ALOX5 P09917 1/20 0.55
PTPN1 P18031 1/20 0.55
PPARG P37231 1/20 0.55
PPARD Q03181 1/20 0.55
ACMSD Q8TDX5 2/20 0.53
PTPN7 P35236 2/20 0.52
DUSP3 P51452 2/20 0.52
ALDH1A1 P00352 2/20 0.52
LMNA P02545 1/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11130424 0.91 QDPR (0.76) QDPRCA2NR3C1TSHRALOX5
SCHEMBL9325871 0.84 PDE4A (0.59) QDPRNR3C1ALDH1A1LMNAMAPT
SCHEMBL10407705 0.83 QDPR (0.66) QDPRCA2NR3C1TSHRALOX5
SCHEMBL8922858 0.83 QDPR (0.50) QDPRCA2NR3C1TSHRALOX5
SCHEMBL14632138 0.83 HTR2A (0.65) QDPRCA2NR3C1TSHR
SCHEMBL11694411 0.82 QDPR (0.50) QDPRCA2NR3C1TSHRALOX5
SCHEMBL11875043 0.82 QDPR (0.50) QDPRCA2NR3C1TSHRALOX5
SCHEMBL21287357 0.82 QDPR (0.50) QDPRCA2NR3C1TSHRALOX5
SCHEMBL14492330 0.81 PDE4A (0.49) QDPRNR3C1ALDH1A1LMNAMAPT
SCHEMBL31545850 0.79 QDPR (0.45) QDPRCA2NR3C1TSHRPTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5654483-A REACTING ALKOXY-SUBSTITUTED CYCLOHEXANONE WITH DIPHENYLAMINE WHILE FORMING CYCLOHEXANONE FROM ALKOXY-SUBSTITUTED PHENOL IN PRESENCE OF SURFACE-SUPPORTED HYDROGEN TRANSFER CATALYST MITSUI TOATSU CHEMICALS, INC. (JP) 1997-08-05 US disclosed