Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677891 | 0.84 | KCNH2 (0.47) | DRD2DRD3KCNH2HTR2A | |
| Hydrochloric Acid SCHEMBL10407836 | 0.83 | KCNH2 (0.46) | DRD2DRD3KCNH2HTR2A | |
| Hydrochloric Acid SCHEMBL10408483 | 0.82 | KCNH2 (0.50) | DRD2DRD3KCNH2HTR2A | |
| Hydrochloric Acid SCHEMBL10407770 | 0.82 | KCNH2 (0.53) | DRD2DRD3KCNH2 | |
| Hydrochloric Acid SCHEMBL10407709 | 0.80 | HTR1A (0.55) | DRD2DRD3KCNH2HTR2A | |
| Hydrochloric Acid SCHEMBL10407613 | 0.80 | KCNH2 (0.50) | DRD2DRD3KCNH2MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL10407824 | 0.80 | DRD4 (0.58) | DRD2DRD3KCNH2HTR2A | |
| SCHEMBL9339570 | 0.79 | DRD2 (0.59) | DRD2DRD3KCNH2HTR2A | |
| SCHEMBL10407558 | 0.79 | HTR1A (0.49) | MEN1KMT2AKCNH2MAPTALDH1A1 | |
| SCHEMBL10407543 | 0.79 | CA1 (0.60) | DRD2DRD3KCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977166-A | ANTIARRHYTHMIC AND ANTIFIBRILLATORY AGENTS | RHONE-POULENC SANTE (FR) | 1990-12-11 | — | — | US | disclosed |