Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 7/20 | 0.61 |
| ▸ | PGR | P06401 | 5/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10408759 | 0.92 | HIF1A (0.63) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL10408758 | 0.91 | NR3C2 (0.64) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL10408757 | 0.91 | NR3C2 (0.64) | NR3C2PGRNR3C1HIF1AKMT2A | |
| Amebucort SCHEMBL142490 | 0.90 | PGR (0.67) | NR3C2PGRNR3C1HIF1AKMT2A | |
| Amebucort SCHEMBL10408572 | 0.90 | PGR (0.67) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL10408760 | 0.90 | PGR (0.63) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL10408761 | 0.90 | PGR (0.63) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL10408662 | 0.89 | NR3C2 (0.75) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL10408661 | 0.89 | NR3C2 (0.75) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL10408593 | 0.89 | PGR (0.66) | NR3C2PGRNR3C1HIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912098-A | Antiinflammatory 6 alpha-methylhydrocortisones | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | disclosed |