Amebucort

Amebucort

SCHEMBL142490

CCCC(=O)O[C@]1(C(=O)COC(C)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C

nearest known ligand 0.67

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 6/20 0.67
▸ AR P10275 4/20 0.67
▸ CHRM1 P11229 3/20 0.67
▸ NR3C2 P08235 6/20 0.62
▸ NR3C1 P04150 3/20 0.62
▸ CYP3A4 P08684 6/20 0.59
▸ HIF1A Q16665 5/20 0.59
▸ CYP2C9 P11712 2/20 0.59
▸ ALDH1A1 P00352 2/20 0.59
▸ TSHR P16473 1/20 0.59
▸ HSD17B10 Q99714 1/20 0.59
▸ KMT2A Q03164 2/20 0.57
▸ LMNA P02545 5/20 0.53
▸ SERPINA6 P08185 1/20 0.53
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ NPSR1 Q6W5P4 2/20 0.51
▸ ABCC4 O15439 1/20 0.51
▸ ABCB11 O95342 1/20 0.51
▸ ESR1 P03372 1/20 0.51
▸ SHBG P04278 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amebucort SCHEMBL10408572 1.00 PGR (0.67) PGRARCHRM1NR3C2NR3C1
SCHEMBL10408593 0.96 PGR (0.66) PGRARCHRM1NR3C2NR3C1
SCHEMBL10408758 0.95 NR3C2 (0.64) PGRARCHRM1NR3C2NR3C1
SCHEMBL10408757 0.95 NR3C2 (0.64) PGRARCHRM1NR3C2NR3C1
SCHEMBL10408599 0.94 PGR (0.61) PGRARCHRM1NR3C2NR3C1
SCHEMBL10408760 0.94 PGR (0.63) PGRARCHRM1NR3C2NR3C1
SCHEMBL10408598 0.94 PGR (0.61) PGRARCHRM1NR3C2NR3C1
SCHEMBL10408761 0.94 PGR (0.63) PGRARCHRM1NR3C2NR3C1
SCHEMBL10409163 0.94 PGR (0.76) PGRARCHRM1NR3C2NR3C1
SCHEMBL10409166 0.94 PGR (0.76) PGRARCHRM1NR3C2NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024189434-A1 USE OF NADOLOL TO TREAT PULMONARY SYMPTOMS ASSOCIATED WITH INFECTIONS WITH SARS-CoV-2 CHRONIC AIRWAY THERAPEUTICS LIMITED (AU) 2024-09-19 — — WO claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 — — CN claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 — — EP claimed
US-4912098-A Antiinflammatory 6 alpha-methylhydrocortisones SCHERING AKTIENGESELLSCHAFT (DE) 1990-03-27 — — US claimed
US-20260124244-A1 MEGAKARYOCYTE DERIVATIVES FOR TREATMENT OF DRY EYE DISEASES STELLULAR BIO, INC. (US) 2026-05-07 — — US disclosed
EP-4646217-A1 MEGAKARYOCYTE DERIVATIVES FOR TREATMENT OF DRY EYE DISEASES Stellular Bio, Inc. (US) 2025-11-12 — — EP disclosed
WO-2024189434-A1 USE OF NADOLOL TO TREAT PULMONARY SYMPTOMS ASSOCIATED WITH INFECTIONS WITH SARS-CoV-2 CHRONIC AIRWAY THERAPEUTICS LIMITED (AU) 2024-09-19 — — WO disclosed
WO-2024148315-A1 MEGAKARYOCYTE DERIVATIVES FOR TREATMENT OF DRY EYE DISEASES STELLULAR BIO, INC. (US) 2024-07-11 — — WO disclosed
CN-116615210-A Novel anuclear cells as a source for the treatment of platelet-rich plasma-dependent disorders 血小板生源说股份有限公司 2023-08-18 — — CN disclosed
US-20230174939-A1 NOVEL ANUCLEATED CELLS AS A SOURCE FOR TREATMENT OF PLATELET RICH PLASMA DEPENDENT DISORDERS STELLULAR BIO, INC. (US) 2023-06-08 — — US disclosed
EP-4149497-A1 NOVEL ANUCLEATED CELLS AS A SOURCE FOR TREATMENT OF PLATELET RICH PLASMA DEPENDENT DISORDERS Platelet Biogenesis, Inc. (US) 2023-03-22 — — EP disclosed
EP-4125947-A1 NOVEL ANUCLEATED CELLS FOR THE TREATMENT OF DISEASES Platelet Biogenesis, Inc. (US) 2023-02-08 — — EP disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 — — US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 — — US disclosed
EP-0098568-B1 CORTICOIDS-CONTAINING PREPARATION FOR TOPICAL APPLICATION SCHERING AKTIENGESELLSCHAFT (DE) 1991-08-28 — — EP disclosed
EP-0098566-B1 CORTICOIDS-CONTAINING PREPARATION FOR TOPICAL APPLICATION SCHERING AKTIENGESELLSCHAFT (DE) 1991-08-21 — — EP disclosed
US-4918065-A ANTIINFLAMMATORY AGENT SCHERING AKTIENGESELLSCHAFT (DE) 1990-04-17 — — US disclosed
US-4912098-A Antiinflammatory 6 alpha-methylhydrocortisones SCHERING AKTIENGESELLSCHAFT (DE) 1990-03-27 — — US disclosed
EP-0098568-A2 Corticoids-containing preparation for topical application SCHERING AKTIENGESELLSCHAFT (DE) 1984-01-18 — — EP disclosed
EP-0098566-A2 Corticoids-containing preparation for topical application SCHERING AKTIENGESELLSCHAFT (DE) 1984-01-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124244-A1 MEGAKARYOCYTE DERIVATIVES FOR TREATMENT OF DRY EYE DISEASES MYH10, PDGFA, MPL PGR 157/4885AR 4167/4885CHRM1 1821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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