Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042326 | 0.87 | KMT2A (0.66) | ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL1912854 | 0.86 | KMT2A (0.62) | ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL28753718 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KMT2AKDM4EMCHR1HTR2A | |
| SCHEMBL14416826 | 0.83 | ALDH1A1 (0.51) | ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL23439634 | 0.82 | GAA (0.63) | ALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL109279 | 0.82 | ALDH1A1 (0.67) | ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL1134127 | 0.82 | CHRM2 (0.74) | ALDH1A1KMT2AKDM4EHTR2AMEN1 | |
| SCHEMBL647938 | 0.81 | ALDH1A1 (0.70) | ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL1038949 | 0.80 | KMT2A (0.81) | ALDH1A1KMT2AKDM4EHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL6122475 | 0.80 | CHRM2 (0.72) | ALDH1A1KMT2AKDM4EHTR2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480941-B1 | UREA DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | AMBRILIA BIOPHARMA INC (CA) | 2011-01-26 | — | — | EP | disclosed |
| EP-1480941-A2 | UREA DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | Procyon Biopharma Inc. (CA) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074467-A2 | UREA DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | PROCYON BIOPHARMA INC. (CA) | 2003-09-12 | — | — | WO | disclosed |
| US-6528532-B1 | Benzenesulfonamide group | PHARMACOR INC. (CA) | 2003-03-04 | — | — | US | disclosed |