Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 13/20 | 0.65 |
| ▸ | CCKAR | P32238 | 11/20 | 0.65 |
| ▸ | NOTCH1 | P46531 | 3/20 | 0.55 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.55 |
| ▸ | NOTCH3 | Q9UM47 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642206 | 0.83 | CCKBR (0.76) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL5656206 | 0.82 | CCKBR (0.74) | CCKBRCCKAR | |
| SCHEMBL644153 | 0.82 | CCKBR (0.74) | CCKBRCCKAR | |
| SCHEMBL8774740 | 0.82 | CCKBR (0.74) | CCKBRCCKAR | |
| SCHEMBL643257 | 0.82 | CCKBR (0.64) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL12693563 | 0.81 | NOTCH1 (0.75) | CCKBRCCKARNOTCH1RBPJNOTCH3 | |
| SCHEMBL12693561 | 0.81 | NOTCH1 (0.75) | CCKBRCCKARNOTCH1RBPJNOTCH3 | |
| SCHEMBL12700015 | 0.79 | NOTCH1 (0.71) | CCKBRCCKARNOTCH1RBPJNOTCH3 | |
| SCHEMBL12693586 | 0.79 | NOTCH1 (0.71) | CCKBRCCKARNOTCH1RBPJNOTCH3 | |
| SCHEMBL9526556 | 0.79 | CCKAR (1.00) | CCKBRCCKARNOTCH1RBPJ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4970207-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-11-13 | — | — | US | disclosed |