Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774740 | 1.00 | CCKBR (0.74) | CCKBRCCKAR | |
| SCHEMBL644153 | 1.00 | CCKBR (0.74) | CCKBRCCKAR | |
| SCHEMBL644305 | 0.89 | CCKBR (0.69) | CCKBRCCKAR | |
| SCHEMBL11981874 | 0.88 | CCKBR (0.62) | CCKBRCCKAR | |
| SCHEMBL8672699 | 0.88 | CCKBR (0.62) | CCKBRCCKAR | |
| SCHEMBL8535202 | 0.87 | CCKBR (0.67) | CCKBRCCKAR | |
| SCHEMBL8535205 | 0.87 | CCKBR (0.67) | CCKBRCCKAR | |
| SCHEMBL642206 | 0.86 | CCKBR (0.76) | CCKBRCCKAR | |
| SCHEMBL9526556 | 0.86 | CCKAR (1.00) | CCKBRCCKAR | |
| SCHEMBL8746538 | 0.86 | CCKAR (1.00) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641781-B1 | Benzodiazepine CGRP receptor antagonists | MERCK SHARP & DOHME (US) | 2013-03-06 | — | — | EP | disclosed |
| US-7196079-B2 | Benzodiazepine CGRP receptor antagonists | MERCK & CO, INC. (US) | 2007-03-27 | — | — | US | disclosed |
| US-20060148790-A1 | Benzodiazepine cgrp receptor antagonists | MERCK SHARP & DOHME LLC | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148790-A1 | Benzodiazepine cgrp receptor antagonists | BDKRB1, CCKBR, BDKRB2 | CCKBR 2/4885CCKAR 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.