Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688781 | 1.00 | MEN1 (0.43) | MEN1KMT2APOLBL3MBTL1KDM4E | |
| SCHEMBL9689658 | 0.81 | KMT2A (0.49) | MEN1KMT2APOLBL3MBTL1KDM4E | |
| SCHEMBL10409069 | 0.81 | KMT2A (0.49) | MEN1KMT2APOLBL3MBTL1KDM4E | |
| SCHEMBL10414316 | 0.77 | TSHR (0.44) | MEN1KMT2AL3MBTL1KDM4ETDP1 | |
| SCHEMBL7298558 | 0.77 | TSHR (0.44) | MEN1KMT2AL3MBTL1KDM4ETDP1 | |
| SCHEMBL5071942 | 0.73 | MEN1 (0.56) | MEN1KMT2APOLBL3MBTL1KDM4E | |
| SCHEMBL29396391 | 0.72 | TDP1 (0.62) | MEN1KMT2APOLBL3MBTL1KDM4E | |
| SCHEMBL1179747 | 0.72 | TDP1 (0.62) | MEN1KMT2APOLBL3MBTL1KDM4E | |
| SCHEMBL5071088 | 0.69 | TUBB1 (0.64) | CYP19A1PTGS2TUBB4ATUBBTUBA3C | |
| SCHEMBL9689630 | 0.69 | KDM4E (0.40) | MEN1KMT2APOLBL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4958026-A | HYPOTENSIVE AGENTS | SCHERING AKTIENGESLLSCHAFT (DE) | 1990-09-18 | — | — | US | disclosed |