Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10409069 | 1.00 | KMT2A (0.49) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL13602996 | 0.88 | MAPT (0.46) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL7408707 | 0.86 | PRMT1 (0.49) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL7408714 | 0.86 | PRMT1 (0.49) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL9688781 | 0.81 | MEN1 (0.43) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL10409130 | 0.81 | MEN1 (0.43) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL5071942 | 0.78 | MEN1 (0.56) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL1179747 | 0.77 | TDP1 (0.62) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL29396391 | 0.77 | TDP1 (0.62) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL30628910 | 0.77 | MAPT (0.51) | KMT2AMEN1MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189473-B1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-05-27 | — | — | EP | disclosed |
| US-4958026-A | HYPOTENSIVE AGENTS | SCHERING AKTIENGESLLSCHAFT (DE) | 1990-09-18 | — | — | US | disclosed |