Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688631 | 0.84 | POLB (0.43) | KDM4EPOLBCTDSP1TDP1L3MBTL1 | |
| SCHEMBL7292776 | 0.75 | HTR1A (0.46) | KDM4ETDP1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10347630 | 0.74 | SMN1; SMN2 (0.62) | SIGMAR1EBPTMEM97 | |
| SCHEMBL1179747 | 0.74 | TDP1 (0.62) | KDM4EPOLBCTDSP1TDP1L3MBTL1 | |
| SCHEMBL29396391 | 0.74 | TDP1 (0.62) | KDM4EPOLBCTDSP1TDP1L3MBTL1 | |
| SCHEMBL9688926 | 0.73 | HTR1A (0.46) | SIGMAR1EBPTMEM97 | |
| SCHEMBL13181024 | 0.71 | ALDH1A1 (0.47) | KDM4EPOLBCTDSP1TDP1L3MBTL1 | |
| SCHEMBL10753475 | 0.71 | AOC3 (0.51) | SIGMAR1EBPTMEM97 | |
| SCHEMBL10959824 | 0.71 | AOC3 (0.48) | SIGMAR1EBPTMEM97 | |
| SCHEMBL10347652 | 0.70 | SIGMAR1 (0.39) | SIGMAR1EBPTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189473-B1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-05-27 | — | — | EP | disclosed |
| US-4958026-A | HYPOTENSIVE AGENTS | SCHERING AKTIENGESLLSCHAFT (DE) | 1990-09-18 | — | — | US | disclosed |
| EP-0189473-A1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS. | SCHERING AG (DE) | 1986-08-06 | — | — | EP | disclosed |
| WO-1986001204-A1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-02-27 | — | — | WO | disclosed |