Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688869 | 0.81 | DRD2 (0.50) | — | |
| SCHEMBL9689788 | 0.79 | HTR2A (0.51) | HTR2AHTR2B | |
| SCHEMBL9688860 | 0.74 | SIGMAR1 (0.41) | SIGMAR1EBPTMEM97HTR1AHTR1D | |
| SCHEMBL10959196 | 0.69 | SIGMAR1 (0.70) | SIGMAR1EBPTMEM97 | |
| SCHEMBL8589988 | 0.65 | SIGMAR1 (0.56) | SIGMAR1EBPTMEM97 | |
| SCHEMBL11517042 | 0.64 | SIGMAR1 (0.82) | SIGMAR1EBPTMEM97HTR2AHTR2B | |
| SCHEMBL9689118 | 0.62 | DRD2 (0.40) | SIGMAR1EBPTMEM97 | |
| Hydrochloric Acid SCHEMBL10347579 | 0.62 | SIGMAR1 (0.59) | SIGMAR1EBPTMEM97HTR1AHTR1D | |
| SCHEMBL24000179 | 0.62 | GRIN2D (0.54) | — | |
| SCHEMBL30088998 | 0.62 | GRIN2D (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4958026-A | HYPOTENSIVE AGENTS | SCHERING AKTIENGESLLSCHAFT (DE) | 1990-09-18 | — | — | US | disclosed |
| EP-0189473-A1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS. | SCHERING AG (DE) | 1986-08-06 | — | — | EP | disclosed |
| WO-1986001204-A1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-02-27 | — | — | WO | disclosed |