SCHEMBL10409137

SCHEMBL10409137

CC(CC(F)(F)F)c1cccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
ADRA2C P18825 5/20 0.45
SLC6A4 P31645 3/20 0.45
CASR P41180 3/20 0.45
SLC6A2 P23975 2/20 0.45
HTR2C P28335 2/20 0.45
OPRM1 P35372 2/20 0.45
DRD3 P35462 2/20 0.45
MLNR O43193 1/20 0.45
ABCB11 O95342 1/20 0.45
ADRB1 P08588 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
CYP2D6 P10635 1/20 0.45
CHRM1 P11229 1/20 0.45
DRD2 P14416 1/20 0.45
CHRM3 P20309 1/20 0.45
GLRA1 P23415 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15211048 0.77 TSHR (0.55) CYP2C9ALDH1A1CYP1A2CYP2C19ADRA2C
SCHEMBL2127427 0.77 TSHR (0.55) CYP2C9ALDH1A1CYP1A2CYP2C19ADRA2C
SCHEMBL28422249 0.76 HTR2A (0.51) CYP2C9ALDH1A1CYP1A2CYP2C19ADRA2C
SCHEMBL3412393 0.76 CYP1A2 (0.50) CYP2C9ALDH1A1CYP1A2CYP2C19ADRA2C
SCHEMBL29484444 0.76 HTR2A (0.51) CYP2C9ALDH1A1CYP1A2CYP2C19ADRA2C
SCHEMBL29110837 0.76 ALDH1A1 (0.50) CYP2C9ALDH1A1CYP1A2CYP2C19ADRA2C
SCHEMBL3412391 0.76 ALDH1A1 (0.50) CYP2C9ALDH1A1CYP1A2CYP2C19ADRA2C
SCHEMBL3410469 0.76 ALDH1A1 (0.50) CYP2C9ALDH1A1CYP1A2CYP2C19ADRA2C
SCHEMBL3410473 0.76 ALDH1A1 (0.50) CYP2C9ALDH1A1CYP1A2CYP2C19ADRA2C
SCHEMBL264495 0.76 ALDH1A1 (0.50) CYP2C9ALDH1A1CYP1A2CYP2C19ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4956390-A FOR CARRYING GASES IN ARTIFICIAL BLOOD AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-09-11 US disclosed
US-4925992-A VAPOR PHASE SOLDERING FLUID AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-05-15 US disclosed
US-4901910-A FOR HEATING AND MELTING AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-02-20 US disclosed
US-4885414-A OF DECAHYDRONAPHTHALENE; NONTOXIC, SHARP BOILING POINT; VAPOR PHASE SOLDERING, ELECTRONICS UNIVERSITY OF PENNSYLVANIA 1989-12-05 US disclosed
US-4881682-A Vapor phase soldering with perfluorinated butyl derivative compounds AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-11-21 US disclosed
US-4873315-A OF DECAHYDRONAPHTHALENE; ELECTRONICS, SYNTHETIC BLOOD, DIAGNOS TIC FLUIDS AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-10-10 US disclosed
US-4849553-A SOLDERING, HYDRAULIC FLUIDS, HEAT TRANSFER AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-07-18 US disclosed
US-4396785-A DIELECTRICS, ALKYLATION KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-08-02 US disclosed