SCHEMBL10409209

SCHEMBL10409209

Cc1ccccc1/N=N/c1ccc(N)cc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.56
MAPK1 P28482 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
TDP1 Q9NUW8 3/20 0.56
TP53 P04637 2/20 0.56
TSHR P16473 2/20 0.56
ALDH1A1 P00352 4/20 0.53
MAPT P10636 4/20 0.53
RAB9A P51151 4/20 0.53
KMT2A Q03164 4/20 0.53
NPC1 O15118 4/20 0.53
MEN1 O00255 3/20 0.53
KDM4E B2RXH2 1/20 0.53
CYP1A2 P05177 1/20 0.53
POLB P06746 1/20 0.53
ATM Q13315 1/20 0.53
SIGMAR1 Q99720 4/20 0.51
GRIN2D O15399 2/20 0.51
GRIN3B O60391 2/20 0.51
GRIN1 Q05586 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9319051 1.00 CYP3A4 (0.56) CYP3A4MAPK1SMN1; SMN2TDP1TP53
SCHEMBL11685094 0.89 ALDH1A1 (0.61) CYP3A4MAPK1SMN1; SMN2TDP1TP53
SCHEMBL9611204 0.89 ALDH1A1 (0.61) CYP3A4MAPK1SMN1; SMN2TDP1TP53
SCHEMBL11844658 0.88 CYP3A4 (0.56) CYP3A4MAPK1SMN1; SMN2TDP1TP53
Hydrochloric Acid SCHEMBL25294171 0.87 TDP1 (0.64) CYP3A4MAPK1SMN1; SMN2TDP1TP53
SCHEMBL11780439 0.85 MAPT (0.50) CYP3A4MAPK1SMN1; SMN2TDP1TP53
SCHEMBL11780445 0.85 MAPT (0.50) CYP3A4MAPK1SMN1; SMN2TDP1TP53
SCHEMBL10494627 0.85 TDP1 (0.66) CYP3A4MAPK1SMN1; SMN2TDP1TP53
SCHEMBL10494630 0.85 TDP1 (0.66) CYP3A4MAPK1SMN1; SMN2TDP1TP53
SCHEMBL11779429 0.83 KMT2A (0.52) CYP3A4MAPK1SMN1; SMN2TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290619-A Supported polyolefin catalyst with light responsiveness and preparation method and application thereof 中国石油化工股份有限公司 2024-07-05 CN disclosed
CN-118290300-A Compound, catalyst, olefin polymer and preparation method thereof 中国石油化工股份有限公司 2024-07-05 CN disclosed
US-4921945-A Disazo dyes containing an acetoacetabukube coupling component and a quaternized aminoalkylene aminocarbonyl group bound to it CIBA-GEIGY CORPORATION (US) 1990-05-01 US disclosed
US-4313872-A MONDAZO AND DISAZO DYES CASSELLA AKTIENGESELLSCHAFT (DE) 1982-02-02 US disclosed
US-4145341-A WATER-SOLUBLE AZO DYES CONTAINING DIAMINOPYRIMIDINE COUPLER COMPONENTS BASF AKTIENGESELLSCHAFT (DE) 1979-03-20 US disclosed
US-4083686-A AZO DYES, WASHFASTNESS, PHOTOSTABILITY, SOLVENT RESISTANCE BASF AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed