Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11780439 | 1.00 | MAPT (0.50) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11649694 | 0.87 | CYP3A4 (0.55) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11649691 | 0.87 | CYP3A4 (0.55) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL10409209 | 0.85 | CYP3A4 (0.56) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9319051 | 0.85 | CYP3A4 (0.56) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9611204 | 0.83 | ALDH1A1 (0.61) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11685094 | 0.83 | ALDH1A1 (0.61) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL10942486 | 0.82 | TDP1 (0.61) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL10942481 | 0.82 | TDP1 (0.61) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11783424 | 0.79 | MAPT (0.46) | MAPTRAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956264-A | Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |