SCHEMBL10409254

SCHEMBL10409254

CCc1cc(Br)ccc1NCCOC

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 3/20 0.44
HPGD P15428 2/20 0.44
LMNA P02545 1/20 0.43
KDM4E B2RXH2 4/20 0.41
GLA P06280 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HCAR3 P49019 1/20 0.41
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
THRB P10828 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NCF1 P14598 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10408210 0.91 PTGER4 (0.46) PTGER4HPGDLMNAKDM4EALDH1A1
SCHEMBL10408256 0.82 ALDH1A1 (0.40) HPGDLMNAKDM4EALDH1A1RAB9A
SCHEMBL8293173 0.79 MAPK1 (0.44) HPGDLMNAKDM4EGLAL3MBTL1
SCHEMBL15774438 0.79 PTGER4 (0.60) PTGER4HPGDLMNAKDM4EGLA
SCHEMBL10409284 0.79 CNR2 (0.49) LMNAHCAR3MAPK1
SCHEMBL10408039 0.78 KDM4E (0.40) PTGER4HPGDLMNAKDM4EALDH1A1
SCHEMBL10409262 0.78 ALDH1A1 (0.48) HPGDLMNAKDM4EL3MBTL1ALDH1A1
SCHEMBL10408187 0.77 CNR2 (0.48) LMNAHCAR3MAPK1
SCHEMBL10408673 0.77 CNR2 (0.48) LMNAHCAR3MAPK1
SCHEMBL15635917 0.77 APEX1 (0.67) PTGER4HPGDKDM4EGLAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4925984-A REACTION WITH BROMINE IN SOLUTION ETHYL CORPORATION (US) 1990-05-15 US disclosed