Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10409579 | 0.98 | SIGMAR1 (0.55) | SIGMAR1DPP7MEN1KMT2APOLB | |
| SCHEMBL10409520 | 0.98 | SIGMAR1 (0.55) | SIGMAR1DPP7MEN1KMT2APOLB | |
| Maleic Acid SCHEMBL10409470 | 0.91 | SIGMAR1 (0.48) | SIGMAR1DPP7MEN1KMT2APOLB | |
| Fumaric Acid SCHEMBL10409472 | 0.91 | SIGMAR1 (0.48) | SIGMAR1DPP7MEN1KMT2APOLB | |
| Fumaric Acid SCHEMBL10409412 | 0.90 | POLB (0.48) | SIGMAR1DPP7MEN1KMT2APOLB | |
| Fumaric Acid SCHEMBL10409444 | 0.90 | POLB (0.48) | SIGMAR1DPP7MEN1KMT2APOLB | |
| Maleic Acid SCHEMBL10409408 | 0.90 | POLB (0.48) | SIGMAR1DPP7MEN1KMT2APOLB | |
| Maleic Acid SCHEMBL10409441 | 0.90 | POLB (0.48) | SIGMAR1DPP7MEN1KMT2APOLB | |
| SCHEMBL10410608 | 0.87 | MEN1 (0.74) | SIGMAR1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL14476103 | 0.84 | MEN1 (0.73) | SIGMAR1MEN1KMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895840-A | ANTIARRHYTHMIA AGENTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0295010-A1 | Derivatives of alkylaminoalkyl ureas and cyanoguanidines | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-12-14 | — | — | EP | disclosed |