Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410049 | 1.00 | ALDH1A1 (0.41) | ALDH1A1PKMSMN1; SMN2NPC1CASP3 | |
| SCHEMBL10411182 | 0.78 | EGLN1 (0.38) | ALDH1A1EGLN1 | |
| SCHEMBL10411184 | 0.78 | EGLN1 (0.38) | ALDH1A1EGLN1 | |
| SCHEMBL7557484 | 0.76 | EGLN1 (0.40) | ALDH1A1EGLN1POLB | |
| SCHEMBL10411663 | 0.76 | EGLN1 (0.39) | EGLN1 | |
| SCHEMBL10517235 | 0.76 | HMGCR (0.40) | ALDH1A1EGLN1ESR1 | |
| SCHEMBL8846678 | 0.73 | ADORA2A (0.38) | NPC1RAB9AEGLN1 | |
| SCHEMBL12078694 | 0.73 | SMN1; SMN2 (0.40) | ALDH1A1PKMSMN1; SMN2NPC1CASP3 | |
| SCHEMBL12078696 | 0.73 | SMN1; SMN2 (0.40) | ALDH1A1PKMSMN1; SMN2NPC1CASP3 | |
| SCHEMBL10410206 | 0.72 | HMGCR (0.44) | ALDH1A1EGLN1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929620-A | ANTILIPEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| US-4868185-A | HYPOLIPIDEMIC, ANTICHOLESTEROL | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | disclosed |