Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411184 | 0.86 | EGLN1 (0.38) | EGLN1PTGS2ALDH1A1PTGS1KMT2A | |
| SCHEMBL10411182 | 0.86 | EGLN1 (0.38) | EGLN1PTGS2ALDH1A1PTGS1KMT2A | |
| SCHEMBL8846678 | 0.83 | ADORA2A (0.38) | EGLN1PTGS2PTGS1ADORA2AADORA2B | |
| SCHEMBL8241631 | 0.81 | GCGR (0.44) | EGLN1PTGS2ALDH1A1PTGS1 | |
| SCHEMBL9788393 | 0.80 | PDE4B (0.50) | PTGS2ALDH1A1KMT2AADORA1POLB | |
| SCHEMBL8949995 | 0.77 | ALDH1A1 (0.46) | PTGS2ALDH1A1KMT2A | |
| SCHEMBL10411663 | 0.77 | EGLN1 (0.39) | EGLN1PTGS2PTGS1ADORA2AADORA2B | |
| SCHEMBL10410046 | 0.76 | ALDH1A1 (0.41) | EGLN1ALDH1A1POLB | |
| SCHEMBL10410049 | 0.76 | ALDH1A1 (0.41) | EGLN1ALDH1A1POLB | |
| SCHEMBL10410199 | 0.72 | EGLN1 (0.48) | EGLN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705837-B1 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-5744604-A | Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| US-5677455-A | Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0705837-A2 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1996-04-10 | — | — | EP | disclosed |
| US-4929620-A | ANTILIPEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| CN-1036954-A | The pyrimidine that replaces | BAYER AG (DE) | 1989-11-08 | — | — | CN | disclosed |
| US-4868185-A | HYPOLIPIDEMIC, ANTICHOLESTEROL | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0330057-A2 | Substituted pyrimidines | BAYER AG (DE) | 1989-08-30 | — | — | EP | disclosed |