Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457332 | 0.93 | LMNA (0.53) | TDP1LMNAMAPTSTS | |
| SCHEMBL7455946 | 0.93 | LMNA (0.53) | TDP1LMNAMAPTSTS | |
| SCHEMBL24330535 | 0.90 | TDP1 (0.53) | TDP1LMNAHPGDSTS | |
| SCHEMBL397968 | 0.83 | CYP4F2 (0.51) | CA1CA2CA12CA9LMNA | |
| SCHEMBL14659554 | 0.83 | TDP1 (0.46) | TDP1CA1CA2LMNA | |
| SCHEMBL10674511 | 0.81 | TDP1 (0.45) | TDP1CA1CA2LMNAMAPT | |
| SCHEMBL15830892 | 0.80 | LMNA (0.54) | TDP1LMNAMAPTSTS | |
| SCHEMBL460642 | 0.79 | CYP3A4 (0.47) | TDP1LMNAMAPTHPGD | |
| SCHEMBL782048 | 0.79 | TDP1 (0.61) | TDP1LMNAMAPTHPGD | |
| SCHEMBL5790462 | 0.79 | TDP1 (0.51) | TDP1CA1CA2CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957988-A | Process and polymers for the production of images | CIBA-GEIGY CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |