SCHEMBL14659554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10410092	0.83	TDP1 (0.53)	TDP1CA1CA2LMNA
	SCHEMBL24330535	0.82	TDP1 (0.53)	TDP1LMNATSHRMAPK1RAB9A
	SCHEMBL16784390	0.81	TDP1 (0.39)	TDP1CA1CA2KDM4EALDH1A1
	SCHEMBL397968	0.81	CYP4F2 (0.51)	CA1CA2KDM4EALDH1A1LMNA
	SCHEMBL7455946	0.80	LMNA (0.53)	TDP1ALDH1A1LMNATSHRRAB9A
	SCHEMBL7457332	0.80	LMNA (0.53)	TDP1ALDH1A1LMNATSHRRAB9A
	SCHEMBL14659582	0.79	ALDH1A1 (0.60)	TDP1CA1CA2KDM4EALDH1A1
	SCHEMBL10674511	0.79	TDP1 (0.45)	TDP1CA1CA2ALDH1A1LMNA
	SCHEMBL12176926	0.78	HSPD1 (0.55)	TDP1CA1CA2ALDH1A1TSHR
	SCHEMBL14666797	0.78	LMNA (0.62)	KDM4ELMNARAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.