Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661641 | 1.00 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL10410872 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL10365359 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL9661945 | 0.79 | NPC1 (0.44) | MEN1KMT2ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL10429290 | 0.79 | NPC1 (0.44) | MEN1KMT2ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL9661654 | 0.79 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL9661947 | 0.79 | KMT2A (0.42) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10366847 | 0.79 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10366849 | 0.79 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10429282 | 0.79 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956470-A | BACTERICIDES, FUNGICIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1990-09-11 | — | — | US | disclosed |
| US-4908363-A | Antiinflammatory agents | HOFFMANN-LA ROCHE INC. (US) | 1990-03-13 | — | — | US | disclosed |
| US-4814332-A | PARASITICIDES | HOFFMAN-LA ROCHE INC. (US) | 1989-03-21 | — | — | US | disclosed |