Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661945 | 1.00 | NPC1 (0.44) | NPC1RAB9AALOX15MEN1KMT2A | |
| SCHEMBL9661641 | 0.79 | MEN1 (0.54) | NPC1RAB9AALOX15MEN1KMT2A | |
| SCHEMBL10410397 | 0.79 | MEN1 (0.54) | NPC1RAB9AALOX15MEN1KMT2A | |
| SCHEMBL9661947 | 0.76 | KMT2A (0.42) | NPC1RAB9AALOX15MEN1KMT2A | |
| SCHEMBL10366849 | 0.76 | MEN1 (0.42) | NPC1RAB9AALOX15MEN1KMT2A | |
| SCHEMBL10548382 | 0.76 | RAB9A (0.41) | NPC1RAB9AALOX15MEN1KMT2A | |
| SCHEMBL10366847 | 0.76 | MEN1 (0.42) | NPC1RAB9AALOX15MEN1KMT2A | |
| SCHEMBL9661654 | 0.76 | MEN1 (0.42) | NPC1RAB9AALOX15MEN1KMT2A | |
| SCHEMBL10548376 | 0.76 | RAB9A (0.41) | NPC1RAB9AALOX15MEN1KMT2A | |
| SCHEMBL10429282 | 0.76 | MEN1 (0.42) | NPC1RAB9AALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908363-A | Antiinflammatory agents | HOFFMANN-LA ROCHE INC. (US) | 1990-03-13 | — | — | US | disclosed |