Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411257 | 0.85 | SLC6A2 (0.49) | SLC6A2SLC6A3ALDH1A1MEN1KMT2A | |
| SCHEMBL10391072 | 0.85 | SLC6A2 (0.65) | SLC6A2SLC6A3ALDH1A1MEN1KMT2A | |
| SCHEMBL9796840 | 0.85 | SLC6A2 (0.65) | SLC6A2SLC6A3ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9796932 | 0.84 | SLC6A2 (0.64) | SLC6A2SLC6A3ALDH1A1MEN1KMT2A | |
| SCHEMBL10390983 | 0.84 | SLC6A2 (0.53) | SLC6A2SLC6A3ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10391005 | 0.84 | SLC6A2 (0.64) | SLC6A2SLC6A3ALDH1A1MEN1KMT2A | |
| SCHEMBL10409601 | 0.83 | L3MBTL1 (0.53) | SLC6A2SLC6A3ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10391080 | 0.83 | SLC6A2 (0.52) | SLC6A2SLC6A3ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9596287 | 0.82 | L3MBTL1 (0.52) | SLC6A2SLC6A3ALDH1A1MEN1KMT2A | |
| SCHEMBL10701944 | 0.81 | MEN1 (0.48) | SLC6A2SLC6A3ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933442-A | 1-(acetylaminophenyl)-2-aminopropanone derivatives and central nervous system antidepressant compositions | LABORATOIRE L. LAFON (FR) | 1990-06-12 | — | — | US | claimed |