Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.41 |
| ▸ | CHRNG | P07510 | 4/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.41 |
| ▸ | CHRND | Q07001 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597385 | 0.85 | SLC6A3 (0.61) | SLC6A3ALDH1A1KDM4EGAASLC6A2 | |
| Hydrochloric Acid SCHEMBL9596538 | 0.84 | SLC6A3 (0.60) | SLC6A3ALDH1A1KDM4EGAASLC6A2 | |
| SCHEMBL9796926 | 0.84 | SLC6A3 (0.60) | SLC6A3ALDH1A1KDM4EGAASLC6A2 | |
| SCHEMBL9360364 | 0.84 | SLC6A3 (0.60) | SLC6A3ALDH1A1KDM4EGAASLC6A2 | |
| Hydrochloric Acid SCHEMBL9797234 | 0.83 | SLC6A3 (0.58) | SLC6A3ALDH1A1KDM4EGAASLC6A2 | |
| Hydrochloric Acid SCHEMBL9796810 | 0.83 | SLC6A3 (0.58) | SLC6A3ALDH1A1KDM4EGAASLC6A2 | |
| SCHEMBL9597221 | 0.83 | SLC6A3 (0.48) | MEN1KMT2ASLC6A3ALDH1A1KDM4E | |
| SCHEMBL10469275 | 0.81 | HRH3 (0.49) | CYP2C19KMT2ASLC6A3ALDH1A1KDM4E | |
| SCHEMBL10410656 | 0.81 | SLC6A2 (0.52) | MEN1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL9596868 | 0.80 | HRH3 (0.48) | CYP2C19KMT2ASLC6A3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174242-B1 | 1-(AMINO-PHENYL)-2-AMINO PROPANON DERIVATIVES, THEIR USE IN THERAPY AND PROCESS FOR THEIR PREPARATION | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1988-01-13 | — | — | EP | claimed |
| EP-0174242-A2 | 1-(Amino-phenyl)-2-amino propanon derivatives, their use in therapy and process for their preparation | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1986-03-12 | — | — | EP | claimed |