Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | MTOR | P42345 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.66 |
| ▸ | MLNR | O43193 | 1/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.66 |
| ▸ | CNR1 | P21554 | 1/20 | 0.66 |
| ▸ | HRH1 | P35367 | 1/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.66 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.66 |
| ▸ | CACNA1C | Q13936 | 9/20 | 0.64 |
| ▸ | CACNA1F | O60840 | 8/20 | 0.64 |
| ▸ | CACNA1D | Q01668 | 8/20 | 0.64 |
| ▸ | CACNA1S | Q13698 | 8/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411081 | 1.00 | ADORA3 (0.66) | ADORA3ADRA1AMTORRAB9ASLC6A3 | |
| SCHEMBL10409941 | 0.95 | CACNA1C (0.69) | ADORA3ADRA1AMTORRAB9ASLC6A3 | |
| SCHEMBL10409943 | 0.95 | CACNA1C (0.69) | ADORA3ADRA1AMTORRAB9ASLC6A3 | |
| SCHEMBL7284259 | 0.94 | ADORA3 (0.74) | ADORA3ADRA1AMTORRAB9ASLC6A3 | |
| SCHEMBL7272697 | 0.92 | ADORA3 (0.73) | ADORA3ADRA1AMTORRAB9ASLC6A3 | |
| SCHEMBL7275429 | 0.90 | CACNA1C (0.70) | ADORA3ADRA1AMTORRAB9ASLC6A3 | |
| SCHEMBL7272469 | 0.89 | CYP1A2 (0.78) | ADORA3ADRA1AMTORRAB9ASLC6A3 | |
| SCHEMBL7529529 | 0.89 | CACNA1B (0.73) | ADORA3MLNRNR1I2CACNA1CCACNA1F | |
| SCHEMBL7529520 | 0.89 | CACNA1B (0.73) | ADORA3MLNRNR1I2CACNA1CCACNA1F | |
| SCHEMBL7274957 | 0.89 | CYP1A2 (0.70) | ADORA3ADRA1AMTORRAB9ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968832-A | INTERMEDIATES FOR CORONARY DILATORS | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1990-11-06 | — | — | US | disclosed |