Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.65 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.64 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.62 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410384 | 0.90 | ALOX5 (0.61) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL10410351 | 0.89 | ALOX5 (0.65) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL1419872 | 0.88 | FFAR1 (0.77) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL1419751 | 0.87 | CYSLTR1 (0.73) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL6088569 | 0.85 | FFAR1 (0.73) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL8800199 | 0.84 | ALOX5 (0.72) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL2167295 | 0.82 | ALOX5 (0.55) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL13772730 | 0.82 | GPBAR1 (0.70) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL1419915 | 0.82 | ALOX5 (0.72) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL8902567 | 0.82 | ALOX5 (0.72) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929626-A | α-substituted 4-(quinolin-2-yl-methoxy)phenylacetic acids and esters and lipoxygenase inhibition therewith | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-29 | — | — | US | disclosed |