SCHEMBL10411985

SCHEMBL10411985

Nc1ccc(S(=O)(=O)CCOP(=O)(O)O)cc1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.39
MMP14 P50281 1/20 0.39
HSD17B10 Q99714 3/20 0.38
ALDH1A1 P00352 3/20 0.38
CA2 P00918 10/20 0.36
CA12 O43570 4/20 0.36
CA1 P00915 4/20 0.36
CA9 Q16790 4/20 0.36
GAA P10253 3/20 0.36
MAPT P10636 3/20 0.36
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.35
RAB9A P51151 2/20 0.35
KMT2A Q03164 2/20 0.35
PKM P14618 1/20 0.35
POLB P06746 1/20 0.34
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
HTT P42858 1/20 0.33
CA4 P22748 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10411687 0.89 CA2 (0.50) HSD17B10ALDH1A1CA2CA12CA1
SCHEMBL7622316 0.83 CTDSP1 (0.37) HSD17B10ALDH1A1CA2GAAMAPT
SCHEMBL6029167 0.81 HSD17B10 (0.45) MMP2MMP14HSD17B10ALDH1A1CA2
SCHEMBL10411983 0.81 HSD17B10 (0.41) MMP2MMP14HSD17B10ALDH1A1CA2
SCHEMBL8899784 0.80 GAA (0.46) MMP2MMP14ALDH1A1CA2CA12
SCHEMBL11670052 0.80 ALDH1A1 (0.41) MMP2MMP14HSD17B10ALDH1A1GAA
SCHEMBL10673232 0.80 CA1 (0.51) MMP2ALDH1A1CA2CA1GAA
SCHEMBL9809412 0.78 ALDH1A1 (0.47) HSD17B10ALDH1A1CA2CA12CA1
SCHEMBL10596598 0.78 ALDH1A1 (0.41) HSD17B10ALDH1A1GAAMAPTKDM4E
SCHEMBL9809401 0.78 CA2 (0.49) HSD17B10ALDH1A1CA2GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4939243-A Water-soluble copper complex disazo compounds containg a chloro triazinylamino group and a group of the vinylsulfone series as fiber-reactive groups and their dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-03 US disclosed