Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411293 | 0.90 | PTGES (0.42) | MAPTPOLBPTGESALOX15TP53 | |
| SCHEMBL10412146 | 0.84 | ALOX15 (0.44) | MAPTPTGESALOX15TP53ALDH1A1 | |
| SCHEMBL10412488 | 0.84 | MAPT (0.42) | MAPTPTGESALOX15TP53SMN1; SMN2 | |
| SCHEMBL10411370 | 0.82 | ALOX15 (0.45) | MAPTPOLBPTGESALOX15TP53 | |
| SCHEMBL10413084 | 0.82 | MAPT (0.39) | MAPTPTGESALOX15TP53ALDH1A1 | |
| SCHEMBL10411301 | 0.82 | NAMPT (0.43) | MAPTTP53ALDH1A1KDM4ELMNA | |
| SCHEMBL10412136 | 0.81 | PTGES (0.43) | MAPTPOLBPTGESTP53LMNA | |
| SCHEMBL10411350 | 0.80 | MAPT (0.39) | MAPTPTGESALOX15TP53NPC1 | |
| SCHEMBL10412940 | 0.79 | POLB (0.45) | MAPTPOLBTP53ALDH1A1LMNA | |
| SCHEMBL10412947 | 0.79 | MAPT (0.50) | MAPTPOLBPTGESTP53CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921871-A | LIPOXYGENASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1990-05-01 | — | — | US | claimed |
| US-4921871-A | LIPOXYGENASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4874758-A | LIPOXYGENASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1989-10-17 | — | — | US | disclosed |
| US-4868195-A | ENZYME INHIBITORS, ANTIALLERGEN, ASTHMA, CARDIOVASCULAR, ANTIINFLAMMATORY | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | disclosed |
| US-4868200-A | LEUKOTRIENES, LIPOXYGENASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | disclosed |
| US-4868205-A | ANTIALLERGENS, ANTIINFLAMMATORY, CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | disclosed |
| US-4868199-A | ENZYME INHIBITORS, ANTIALLERGEN, ASTHMA, CARDIOVASCULAR, ANTIINFLAMMATORY | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | disclosed |
| US-4761424-A | Enolamides, pharmaceutical compositions and methods for treating inflammation | WARNER-LAMBERT COMPANY (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0221345-A1 | Novel enolamides, process for their manufacture and pharmaceutical compositions thereof with an activity as modulators of the arachidonic acid cascade | WARNER-LAMBERT COMPANY (US) | 1987-05-13 | — | — | EP | disclosed |