Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412275 | 1.00 | PLCG1 (1.00) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11773847 | 0.94 | PLCG1 (0.89) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11773967 | 0.92 | PLCG1 (0.86) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11771771 | 0.92 | PLCG1 (0.86) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11182332 | 0.92 | PLCG1 (0.85) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11411672 | 0.92 | PLCG1 (0.85) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11182329 | 0.92 | PLCG1 (0.85) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11411669 | 0.92 | PLCG1 (0.85) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL9655895 | 0.91 | PLCG1 (0.84) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL8766584 | 0.91 | PLCG1 (0.83) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931555-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-06-05 | — | — | US | disclosed |
| US-4435321-A | BACTERICIDES AND INTERMEDIATES FOR 2- OR 3-CEPHEMS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0014567-B1 | PROCESSES FOR PREPARATION OF BETA-LACTAM COMPOUNDS | ELI LILLY AND COMPANY (US) | 1984-01-18 | — | — | EP | disclosed |
| US-4410458-A | GROUP 5B OR 6B METAL COMPOUND OXIDATION CATALYST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-18 | — | — | US | disclosed |
| US-4267340-A | BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | disclosed |
| EP-0014567-A1 | Processes for preparation of beta-lactam compounds | ELI LILLY AND COMPANY (US) | 1980-08-20 | — | — | EP | disclosed |
| US-4211702-A | TRIARYLPHOSPHITE-HALOGEN COMPLEX HALOGENATING AGENT | ELI LILLY AND COMPANY (US) | 1980-07-08 | — | — | US | disclosed |
| US-4159267-A | Novel silyl ester azetidine-2-sulfenate intermediates and process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4091214-A | ALPHA-HYDROXY CARBOXYLIC ACID | ELI LILLY AND COMPANY (US) | 1978-05-23 | — | — | US | disclosed |
| US-4071527-A | Certain benzothiazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-31 | — | — | US | disclosed |
| US-4044002-A | ACYL BROMIDES AND A BROMINE SCAVENGER | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4005074-A | Process for cleaving an imido side chain from penicillins and cephalosporins | ELI LILLY AND COMPANY (US) | 1977-01-25 | — | — | US | disclosed |
| US-4001239-A | CEPHALOSPORIN CLEAVAGE PROCESS | ELI LILLY AND COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3994888-A | Cephalosporin cleavage process | ELI LILLY AND COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | disclosed |
| US-3972774-A | BY AN ESTERASE ENZYME FROM BACILLUS | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |
| US-3944545-A | Process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1976-03-16 | — | — | US | disclosed |