Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11773847 | 0.93 | PLCG1 (0.89) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL10412275 | 0.92 | PLCG1 (1.00) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL10412277 | 0.92 | PLCG1 (1.00) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11771771 | 0.92 | PLCG1 (0.86) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11772200 | 0.91 | PLCG1 (0.72) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11772203 | 0.91 | PLCG1 (0.72) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11648874 | 0.91 | PLCG1 (0.71) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11648872 | 0.91 | PLCG1 (0.71) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11771169 | 0.89 | PLCG1 (0.81) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11774310 | 0.89 | PLCG1 (0.81) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3972774-A | BY AN ESTERASE ENZYME FROM BACILLUS | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |