Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.84 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412277 | 0.91 | PLCG1 (1.00) | PLCG1L3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL10412275 | 0.91 | PLCG1 (1.00) | PLCG1L3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL11773847 | 0.89 | PLCG1 (0.89) | PLCG1L3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL11771771 | 0.87 | PLCG1 (0.86) | PLCG1L3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL11773967 | 0.87 | PLCG1 (0.86) | PLCG1L3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL11654441 | 0.86 | PLCG1 (0.81) | PLCG1L3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL11097617 | 0.86 | PLCG1 (0.81) | PLCG1L3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL11774310 | 0.86 | PLCG1 (0.81) | PLCG1L3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL11672615 | 0.85 | PLCG1 (0.79) | PLCG1L3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL11672611 | 0.85 | PLCG1 (0.79) | PLCG1L3MBTL1ALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268343-B1 | ENZYMATIC PROCESS FOR 3-SUBSTITUTED CEPHALOSPORINS | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 1992-05-27 | — | — | EP | disclosed |
| EP-0268343-A2 | Enzymatic process for 3-substituted cephalosporins | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 1988-05-25 | — | — | EP | disclosed |