Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30464707 | 0.71 | ALOX5 (0.42) | — | |
| SCHEMBL28360773 | 0.71 | ALOX5 (0.42) | — | |
| SCHEMBL11140066 | 0.70 | ALOX5 (0.50) | — | |
| SCHEMBL27480119 | 0.68 | PTGS2 (0.51) | — | |
| SCHEMBL11707644 | 0.68 | PTGS2 (0.51) | — | |
| SCHEMBL106347 | 0.68 | PTGS2 (0.51) | — | |
| SCHEMBL27415887 | 0.68 | PTGS2 (0.51) | — | |
| SCHEMBL27418722 | 0.68 | PTGS2 (0.51) | — | |
| SCHEMBL107574 | 0.68 | PTGS2 (0.51) | — | |
| SCHEMBL11707780 | 0.68 | PTGS2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178413-A1 | Benzimidazoles | BEECHAM GROUP PLC (GB) | 1986-04-23 | — | — | EP | claimed |
| US-4925853-A | Antiinflammatory, antiallergens, antiulcer agents | BEECHAM GROUP PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| EP-0178413-A1 | Benzimidazoles | BEECHAM GROUP PLC (GB) | 1986-04-23 | — | — | EP | disclosed |