Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673706 | 0.98 | POLB (0.46) | KDM4EHSD17B10POLBALDH1A1USP2 | |
| SCHEMBL16904245 | 0.93 | ALDH1A1 (0.40) | KDM4EHSD17B10POLBALDH1A1USP2 | |
| SCHEMBL1777591 | 0.85 | ALDH1A1 (0.48) | KDM4EHSD17B10POLBALDH1A1USP2 | |
| SCHEMBL7195274 | 0.84 | NAAA (0.49) | NAAA | |
| SCHEMBL11884677 | 0.81 | NAAA (0.58) | NAAA | |
| SCHEMBL4056985 | 0.80 | ALDH1A1 (0.42) | KDM4EHSD17B10POLBALDH1A1USP2 | |
| SCHEMBL28392032 | 0.79 | KDM4E (0.48) | KDM4EHSD17B10POLBALDH1A1USP2 | |
| SCHEMBL11093553 | 0.78 | KDM4E (0.52) | KDM4EHSD17B10POLBALDH1A1USP2 | |
| SCHEMBL9813351 | 0.78 | KDM4E (0.52) | KDM4EHSD17B10POLBALDH1A1USP2 | |
| SCHEMBL11091255 | 0.78 | KDM4E (0.52) | KDM4EHSD17B10POLBALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906654-A | Cyclohept[b]indoleakanoic acids, pharmaceutical compositions and use | MERCK FROSST CANADA, INC. (CA) | 1990-03-06 | — | — | US | disclosed |