Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29375092 | 0.94 | ESR1 (0.60) | ESR1ESR2CYP3A4HPGDTSHR | |
| Lithium SCHEMBL30790417 | 0.92 | ESR1 (0.58) | ESR1ESR2CYP3A4HPGDTSHR | |
| SCHEMBL10589338 | 0.89 | ESR1 (0.52) | ESR1ESR2CYP3A4HPGDTSHR | |
| SCHEMBL34468242 | 0.88 | ESR1 (0.54) | ESR1ESR2CYP3A4HPGDTSHR | |
| Bicarbonate SCHEMBL29759563 | 0.87 | ESR1 (0.52) | ESR1ESR2CYP3A4HPGDTSHR | |
| Cyanate SCHEMBL30109364 | 0.85 | ESR1 (0.50) | ESR1ESR2CYP3A4HPGDTSHR | |
| SCHEMBL10412349 | 0.83 | ESR1 (0.52) | ESR1ESR2CYP3A4HPGDTSHR | |
| SCHEMBL298177 | 0.82 | ALOX5 (0.32) | ALDH1A1TYRCA2 | |
| Terephthalic Acid SCHEMBL29759542 | 0.81 | CA2 (0.50) | ESR1ESR2CYP3A4HPGDTSHR | |
| Pyrophosphoric Acid SCHEMBL30675345 | 0.80 | ESR1 (0.44) | ESR1ESR2CYP3A4HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895200-A | 1,3-BIS(4-HYDROXYCUMYL)BENZENE, 1,4-BIS(4-HYDROXYXUMYL)BENZENE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0335816-A2 | Copolyester which is particularly suitable for use in making tire cord | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-10-04 | — | — | EP | disclosed |
| US-4824928-A | BIS/P-HYDROXYCUMYL/BENZENE, PHENYLHYDROQUINONE, TEREPHTHALIC ACID, ANISOTROPIC | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-04-25 | — | — | US | disclosed |