SCHEMBL10412946

SCHEMBL10412946

COCC1OC(=O)N(c2cc(Cl)cc(Cl)c2)C1=O

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
MAOA P21397 2/20 0.34
ALDH1A1 P00352 2/20 0.34
USP2 O75604 1/20 0.34
HSD17B10 Q99714 1/20 0.34
BCL2A1 Q16548 1/20 0.30
DRD2 P14416 1/20 0.30
DRD3 P35462 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11540477 0.83 HSD17B10 (0.40) TSHRMAOAALDH1A1USP2HSD17B10
SCHEMBL10920356 0.74 MAOA (0.61) TSHRMAOAALDH1A1USP2HSD17B10
SCHEMBL10920357 0.74 MAOA (0.61) TSHRMAOAALDH1A1USP2HSD17B10
SCHEMBL19066641 0.70 ALDH1A1 (0.46) TSHRALDH1A1USP2HSD17B10
SCHEMBL3936528 0.70 ALDH1A1 (0.46) TSHRALDH1A1USP2HSD17B10
SCHEMBL412939 0.70 ALDH1A1 (0.46) TSHRALDH1A1USP2HSD17B10
SCHEMBL11850278 0.69 ALDH1A1 (0.33) TSHRMAOAALDH1A1HSD17B10
SCHEMBL9194088 0.68 TSHR (0.36) TSHRMAOAALDH1A1USP2HSD17B10
SCHEMBL9194093 0.68 TSHR (0.36) TSHRMAOAALDH1A1HSD17B10BCL2A1
SCHEMBL10639323 0.67 ALDH1A1 (0.36) TSHRMAOAALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4945112-A Guanidinium compounds and fungicides containing them BASF AKTIENGESELLSCHAFT (DE) 1990-07-31 US disclosed