Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25485423 | 1.00 | USP2 (0.55) | USP2LMNACYP1A2AGTR1HSD17B10 | |
| SCHEMBL11046670 | 0.98 | USP2 (0.53) | USP2LMNACYP1A2AGTR1HSD17B10 | |
| SCHEMBL18805113 | 0.98 | USP2 (0.53) | USP2LMNACYP1A2AGTR1HSD17B10 | |
| SCHEMBL2931768 | 0.98 | USP2 (0.53) | USP2LMNACYP1A2AGTR1HSD17B10 | |
| SCHEMBL15214942 | 0.98 | USP2 (0.53) | USP2LMNACYP1A2AGTR1HSD17B10 | |
| SCHEMBL12883079 | 0.98 | USP2 (0.53) | USP2LMNACYP1A2AGTR1HSD17B10 | |
| SCHEMBL10044032 | 0.98 | USP2 (0.53) | USP2LMNACYP1A2AGTR1HSD17B10 | |
| SCHEMBL18962003 | 0.91 | USP2 (0.55) | USP2LMNACYP1A2AGTR1HSD17B10 | |
| SCHEMBL10412965 | 0.90 | USP2 (0.67) | USP2LMNACYP1A2AGTR1HSD17B10 | |
| SCHEMBL9528975 | 0.89 | USP2 (0.46) | USP2LMNACYP1A2AGTR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-9474810-B2 | Superparamagnetic nanoparticles with PEG substituted α-hydroxy phosphonate shells | GENERAL ELECTRIC COMPANY (US) | 2016-10-25 | — | — | US | disclosed |
| US-9474810-B2 | Superparamagnetic nanoparticles with PEG substituted α-hydroxy phosphonate shells | GENERAL ELECTRIC COMPANY (US) | 2016-10-25 | — | — | US | disclosed |
| US-20160131809-A1 | PHASE DIFFERENCE FILM, POLARIZATION PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2016-05-12 | — | — | US | disclosed |
| US-20160131809-A1 | PHASE DIFFERENCE FILM, POLARIZATION PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2016-05-12 | — | — | US | disclosed |
| US-9251937-B2 | Heat stable nanoparticle preparations and associated methods thereof | GENERAL ELECTRIC COMPANY (US) | 2016-02-02 | — | — | US | disclosed |
| US-9251937-B2 | Heat stable nanoparticle preparations and associated methods thereof | GENERAL ELECTRIC COMPANY (US) | 2016-02-02 | — | — | US | disclosed |
| US-8895068-B2 | Nanoparticle composition and associated methods thereof | GENERAL ELECTRIC COMPANY (US) | 2014-11-25 | — | — | US | disclosed |
| US-8889103-B2 | Diagnostic agent composition and associated methods thereof | GENERAL ELECTRIC COMPANY (US) | 2014-11-18 | — | — | US | disclosed |
| US-20130230463-A1 | SUPERPARAMAGNETIC NANOPARTICLES WITH PEG SUBSTITUTED alpha-HYDROXY PHOSPHONATE SHELLS | GENERAL ELECTRIC COMPANY (US) | 2013-09-05 | — | — | US | disclosed |
| US-20130230463-A1 | SUPERPARAMAGNETIC NANOPARTICLES WITH PEG SUBSTITUTED alpha-HYDROXY PHOSPHONATE SHELLS | GENERAL ELECTRIC COMPANY (US) | 2013-09-05 | — | — | US | disclosed |
| CN-102031178-B | Low sulfur diesel lubricity additive and preparation method thereof | ZIBO RUNBO CHEMICAL MARKETING CO LTD | 2013-07-03 | — | — | CN | disclosed |
| US-20120156141-A1 | NANOPARTICLE COMPOSITION AND ASSOCIATED METHODS THEREOF | GENERAL ELECTRIC COMPANY (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120156142-A1 | DIAGNOSTIC AGENT COMPOSITION AND ASSOCIATED METHODS THEREOF | GENERAL ELECTRIC COMPANY (US) | 2012-06-21 | — | — | US | disclosed |
| CN-102031178-A | Low sulfur diesel lubricity additive and preparation method thereof | WHEELOCK ZIBO CHEMICAL CO LTD | 2011-04-27 | — | — | CN | disclosed |
| EP-0759459-B1 | Thermoplastic resin composition superior in transparency and antistatic property | TEIJIN LTD (JP) | 2001-01-03 | — | — | EP | disclosed |
| US-5849822-A | Thermoplastic resin composition superior in transparency and antistatic property | TEIJIN LIMITED (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0759459-A2 | Thermoplastic resin composition superior in transparency and antistatic property | TEIJIN LIMITED (JP) | 1997-02-26 | — | — | EP | disclosed |
| US-4474963-A | PHASE TRANSFER CATALYSTS | W. R. GRACE & CO. (US) | 1984-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120156142-A1 | DIAGNOSTIC AGENT COMPOSITION AND ASSOCIATED METHODS THEREOF | PHOSPHO1, PHAX, PIK3CA | USP2 1884/4885LMNA 778/4885CYP1A2 4196/4885 |
| US-20130230463-A1 | SUPERPARAMAGNETIC NANOPARTICLES WITH PEG SUBSTITUTED alpha-HYDROXY PHOSPHONATE SHELLS | HAMP, FTH1, TFRC | USP2 1217/4885LMNA 2281/4885CYP1A2 3531/4885 |
| US-20120156141-A1 | NANOPARTICLE COMPOSITION AND ASSOCIATED METHODS THEREOF | PHOSPHO1, PIK3CA, PTEN | USP2 2226/4885LMNA 553/4885CYP1A2 4538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.