Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412513 | 0.92 | HTR1A (0.52) | HTR1ASLC6A4ADRA2AADRA2BADRA2C | |
| SCHEMBL9828847 | 0.91 | HTR1A (0.54) | HTR1ASLC6A4ADRA2AADRA2BADRA2C | |
| SCHEMBL10647445 | 0.90 | HTR1A (0.52) | HTR1ASLC6A4 | |
| SCHEMBL10413254 | 0.90 | HTR1A (0.50) | HTR1ASLC6A4ADRA2AADRA2BADRA2C | |
| SCHEMBL10414111 | 0.89 | HTR1A (0.54) | HTR1ASLC6A4 | |
| SCHEMBL10413623 | 0.89 | HTR1D (0.53) | HTR1ASLC6A4 | |
| SCHEMBL10412928 | 0.88 | HTR1D (0.54) | HTR1ASLC6A4 | |
| SCHEMBL10413241 | 0.88 | HTR1A (0.51) | HTR1ASLC6A4 | |
| SCHEMBL10414179 | 0.88 | HTR1A (0.51) | HTR1ASLC6A4 | |
| SCHEMBL10412989 | 0.86 | HTR1A (0.53) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916143-A | Hydroxyindole esters | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | disclosed |