Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828847 | 0.95 | HTR1A (0.54) | HTR1ASLC6A4 | |
| SCHEMBL10646937 | 0.93 | HTR1A (0.50) | HTR1A | |
| SCHEMBL10652767 | 0.93 | DRD2 (0.48) | — | |
| SCHEMBL10652180 | 0.92 | HTR1A (0.48) | HTR1ASLC6A4 | |
| SCHEMBL10414179 | 0.92 | HTR1A (0.51) | HTR1ASLC6A4 | |
| SCHEMBL10414111 | 0.91 | HTR1A (0.54) | HTR1ASLC6A4 | |
| SCHEMBL10413623 | 0.91 | HTR1D (0.53) | HTR1ASLC6A4 | |
| SCHEMBL10412928 | 0.90 | HTR1D (0.54) | HTR1ASLC6A4 | |
| SCHEMBL10413761 | 0.90 | HTR1A (0.51) | HTR1ASLC6A4 | |
| SCHEMBL10413241 | 0.90 | HTR1A (0.51) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144012-B1 | INDOLE DERIVATIVES | MERCK PATENT GmbH (DE) | 1988-03-16 | — | — | EP | disclosed |
| EP-0144012-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1985-06-12 | — | — | EP | disclosed |