Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 5/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413945 | 1.00 | ADRB2 (0.48) | ADRB2KDM4EALDH1A1KMT2ADPP4 | |
| SCHEMBL10413369 | 0.85 | ADRB2 (0.47) | ADRB2KDM4EALDH1A1KMT2ADPP4 | |
| SCHEMBL5809336 | 0.83 | ADRB2 (0.53) | ADRB2KDM4EALDH1A1KMT2ADPP4 | |
| SCHEMBL9730924 | 0.82 | KDM4E (0.55) | ADRB2KDM4EALDH1A1KMT2AHSD17B10 | |
| SCHEMBL10412661 | 0.82 | ADRB2 (0.44) | ADRB2KDM4EALDH1A1KMT2ADPP4 | |
| SCHEMBL10412660 | 0.82 | ADRB2 (0.44) | ADRB2KDM4EALDH1A1KMT2ADPP4 | |
| SCHEMBL10473178 | 0.81 | ADRB2 (0.47) | ADRB2KDM4EALDH1A1KMT2ADPP4 | |
| SCHEMBL10413898 | 0.81 | ADRB2 (0.44) | ADRB2KDM4EALDH1A1KMT2ADPP4 | |
| SCHEMBL5422476 | 0.81 | ADRB2 (0.51) | ADRB2KDM4EALDH1A1KMT2ADPP4 | |
| SCHEMBL10471171 | 0.80 | ADRB2 (0.46) | ADRB2KDM4EALDH1A1KMT2ADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4945160-A | Preparation of certain 7-substituted quinolones | WARNER-LAMBERT COMPANY (US) | 1990-07-31 | — | — | US | disclosed |