Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692723 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15HSD17B10APP | |
| SCHEMBL5644465 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TSHRALOX15HSD17B10APP | |
| SCHEMBL21359219 | 0.74 | MAPT (0.47) | ALDH1A1TSHRALOX15HSD17B10APP | |
| SCHEMBL5640688 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TSHRALOX15HSD17B10APP | |
| SCHEMBL19425812 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TSHRALOX15HSD17B10APP | |
| SCHEMBL23089861 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TSHRALOX15HSD17B10APP | |
| SCHEMBL28537509 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TSHRALOX15HSD17B10APP | |
| SCHEMBL1041171 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TSHRALOX15HSD17B10APP | |
| SCHEMBL9322910 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TSHRALOX15HSD17B10APP | |
| SCHEMBL7744331 | 0.73 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15HSD17B10APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963566-A | ANTIULCER AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |