Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30123613 | 0.84 | ALDH1A1 (0.45) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL23926483 | 0.84 | ALDH1A1 (0.45) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL3885663 | 0.82 | ALDH1A1 (0.46) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL11149905 | 0.78 | S100B (0.66) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL2313495 | 0.78 | ALDH1A1 (0.52) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL31361979 | 0.78 | ALDH1A1 (0.52) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL7692723 | 0.78 | ALDH1A1 (0.50) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL21586818 | 0.77 | HDAC1 (0.42) | ALDH1A1MAPK1TDP1CA12CA1 | |
| SCHEMBL8282330 | 0.77 | CA12 (0.46) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL8281091 | 0.77 | SMN1; SMN2 (0.44) | ALDH1A1MAPK1TP53CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160243059-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DEGENERATIVE BRAIN DISEASE COMPRISING MULTI-TARGETING COMPOUNDS | UNIST ACADEMY-INDUSTRY RESEARCH CORPORATION (KR) | 2016-08-25 | — | — | US | claimed |
| US-20160243059-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DEGENERATIVE BRAIN DISEASE COMPRISING MULTI-TARGETING COMPOUNDS | UNIST ACADEMY-INDUSTRY RESEARCH CORPORATION (KR) | 2016-08-25 | — | — | US | disclosed |
| WO-2008124550-A1 | PHENOTHIAZIN DERIVATIVES FOR ANTIVIRAL TREATMENTS | PROSETTA CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |
| US-6316605-B1 | FOR USE IN RECORDING MATERIALS FOR THERMAL TRANSFER RECORDING, INK JET RECORDING | FUJI PHOTO FILM CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160243059-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DEGENERATIVE BRAIN DISEASE COMPRISING MULTI-TARGETING COMPOUNDS | APP, PSEN1, BACE1 | ALDH1A1 1006/4885ALOX15 65/4885CYP3A4 4370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.