Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.63 |
| ▸ | RXRA | P19793 | 1/20 | 0.58 |
| ▸ | FBP1 | P09467 | 6/20 | 0.53 |
| ▸ | TLR4 | O00206 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104147 | 1.00 | HSP90AA1 (0.63) | HSP90AA1RXRAFBP1TLR4TLR2 | |
| SCHEMBL29925427 | 1.00 | HSP90AA1 (0.63) | HSP90AA1RXRAFBP1TLR4TLR2 | |
| Toluene SCHEMBL27718173 | 0.90 | HSP90AA1 (0.53) | HSP90AA1RXRAFBP1TLR4TLR2 | |
| SCHEMBL10513157 | 0.85 | HSP90AA1 (0.65) | HSP90AA1RXRAFBP1TLR4TLR2 | |
| SCHEMBL10513164 | 0.85 | HSP90AA1 (0.65) | HSP90AA1RXRAFBP1TLR4TLR2 | |
| SCHEMBL10517814 | 0.82 | HSP90AA1 (0.61) | HSP90AA1RXRAFBP1TLR4TLR2 | |
| SCHEMBL17512176 | 0.82 | HSP90AA1 (0.61) | HSP90AA1RXRAFBP1TLR4TLR2 | |
| SCHEMBL17512177 | 0.82 | HSP90AA1 (0.61) | HSP90AA1RXRAFBP1TLR4TLR2 | |
| SCHEMBL4361353 | 0.80 | MAPT (0.61) | HSP90AA1RXRAFBP1TLR4TLR2 | |
| SCHEMBL4307048 | 0.80 | MAPT (0.61) | HSP90AA1RXRAFBP1TLR4TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116613-B | Polysubstituted benzimidazole thiazole and derivative and synthesis method thereof | 湘潭大学 | 2021-04-23 | — | — | CN | claimed |
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | claimed |
| CN-103848830-B | A kind of simple and easy method of synthesis imidazo [1,2-α] pyridine derivate | 淮阴师范学院 | 2016-08-03 | — | — | CN | claimed |
| CN-104277072-B | A kind of preparation method of (E)-2-aryl vinyl phosphate derivatives | JIANGSU CHINASUN SPECIALTY PRODUCTS CO.,LTD. (CN) | 2016-04-13 | — | — | CN | claimed |
| CN-105040398-A | Improved cashmere oxidation bleaching method | NINGXIA ZHONGYIN CASHMERE CO LTD | 2015-11-11 | — | — | CN | claimed |
| CN-104277072-A | Method for preparing (E)-2-aryl vinyl phosphonate derivatives | CHINASUN SPECIALTY PRODUCTS CO LTD | 2015-01-14 | — | — | CN | claimed |
| EP-4627896-A2 | 3D/2D PEROVSKITE SOLAR CELLS | ODTÜ-GÜNAM (TR) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024118031-A2 | 3D/2D PEROVSKITE SOLAR CELLS | ODTÜ-GÜNAM (TR) | 2024-06-06 | — | — | WO | disclosed |
| CN-111217707-B | Preparation method of beta-trans-nitroolefin | 西北师范大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-113509959-A | Preparation method of hollow mesoporous nano silicon spheres for packaging chiral catalyst, product and application thereof | 重庆邮电大学 | 2021-10-19 | — | — | CN | disclosed |
| US-11136296-B2 | Substituted N-arylethyl-2-arylquinoline-4-carboxamides and use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2021-10-05 | — | — | US | disclosed |
| CN-111116613-B | Polysubstituted benzimidazole thiazole and derivative and synthesis method thereof | 湘潭大学 | 2021-04-23 | — | — | CN | disclosed |
| CN-111217707-A | preparation method of β -trans-nitroolefin | 西北师范大学 | 2020-06-02 | — | — | CN | disclosed |
| US-4820734-A | ANALGESICS,ANTIDEPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0138030-B1 | PHENYLETHYLAMINE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-09-30 | — | — | EP | disclosed |
| EP-0138030-A2 | Phenylethylamine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-04-24 | — | — | EP | disclosed |
| US-4148795-A | Dithiocarbamate ester bactericides and fungicides | AMERICAN CYANAMID COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4038288-A | DITHIOCARBAMATE ESTER BACTERICIDES AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
| US-4011230-A | DITHIOCARBAMATE ESTER BACTERICIDES AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-03-08 | — | — | US | disclosed |
| US-3931220-A | FUNGICIDE, BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11136296-B2 | Substituted N-arylethyl-2-arylquinoline-4-carboxamides and use thereof | AADAC, NAT1, EPX | HSP90AA1 2125/4885RXRA 242/4885FBP1 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.