Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21573033 | 0.87 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL10415427 | 0.84 | PTPN1 (0.64) | SMN1; SMN2ALDH1A1NPC1RAB9AAKR1C3 | |
| SCHEMBL275400 | 0.83 | HAO1 (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL19014549 | 0.80 | MEN1 (0.58) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL3553068 | 0.79 | KDM4E (0.56) | ALDH1A1NPC1RAB9AAKR1C3AKR1C2 | |
| SCHEMBL30623333 | 0.79 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL15385104 | 0.79 | KDM4E (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL1317943 | 0.79 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL9700316 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1NPC1RAB9AAKR1C3 | |
| SCHEMBL10456611 | 0.78 | CYP2A6 (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4902799-A | HYPOTENSIVE, HYPOLIPEMIC, ANTIANOXIC, SPASMOLYTIC, PLATELET AGGREGATION INHIBITING, ANTITHROMBOTIC, CALCIUM ANTAGONIZING, NEUROLEPTIC AGENTS | MAGGIONI-WINTHROP S.P.A. (IT) | 1990-02-20 | — | — | US | disclosed |